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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '042c88a8f157f12b4454b7bd820cb31426c36c76b689acd2d813a3cb44efe01a' 
  AND token = 'WPV5NBZJQR83aBuovTD+EFn//M2N3gBZ9h34EF4Qax8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}