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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd6d1048478eb0fdc08d3edc677837db0dc8b920affd57f9e6d62f151de854ab9' 
  AND token = 'vY4k0UUDt/oS6gPCYBICBoiYtM7BENlAAA565SDGi0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}