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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '044ae1d3aa0fbe6d316b162b91dc97181cabea18d62a49d40a62ce3ffbe6586b' 
  AND token = 'ZXFgCBRkSd/an7pra/WQf96CcDe2esnJ11lx7ef1Nrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}