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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a686d84b4ee086d763d2306ffad086815405aaa16036cdc9cc4adad5449ec430' 
  AND token = '3ZMYRF6oF6mRlN8UaSD1OH9lxP5y/3LAdDNCtWt4neA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}