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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49ab6a342349c004bdcef82ec5ac54bff6789b2773e93b065d8af2c2c58752fc' 
  AND token = 'wDTj5LY/EQ3o/HCWtHitm1EdtdvONjxuEi6nenT1UBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}