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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '51499a6b7240ea58f023ceb31b943df1ce64422c96574878e5a5039913ec2e8c' 
  AND token = 'sKywbgMGrznajvUkE/dAVb7osma1M2KoGy325re3ywc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}