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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1189fac2f87acbe359a72a3e701bf35d479a4bf5631a6cf80bab0121664e90c3' 
  AND token = 'e/MQM7kjaSlLOxYdAF7i7oA4E5SHaJBQLkuP7rEgHEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}