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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9e54fbce37664abf1280ecbb7b5c94e9dc298a230e932fda04495003d45cd085' 
  AND token = 'm+EhayvK2BIZM6NMb7b+f0etF/OxmdRnfiaPwL0JobU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}