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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa21388f014f14b6570b1aa9a3c9cd07b654ddbf96f2f12a40b923d4c210bcf5' 
  AND token = 'UOh/23ABsDz26TY3RxRKD0tTXeOQXW6VfShOxJRe7uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}