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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd5d0ebe36bdf0a038d468c780c6ca064de9222b3fe637d5649d34754ce0c2958' 
  AND token = 'JoBb7pSwoqoO7GkNEktMHUo30jkBZ9IxZ6tQQdv20lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}