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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5db646d120af6c562ecfcf38d23d43db7a6412e3ea88cb58d854f63106c95c2c' 
  AND token = 'oOqQcTIRddfgOMhDFUmu2n6d5MCJfnRRIxOlwAZXjx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}