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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fce1bd3272eae28433fde428fa0135f14a912fbeffe9318f3486a3b79cfed07f' 
  AND token = '43dw0RC3aqxJZwYDmGIExymE9VtoZNBxmwde3Meq6Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}