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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c81ddc37f040ca8ec3fd9fd46b654bad2750cd678e52d40fcb165daec0eff212' 
  AND token = 'KAFDNC8EOK7KlhH2QcfnLnUBRFOXcAHaTdd/k8vqpfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}