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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5287f62fd75eaf06ddb065e9e189797d5c6f592394a1b05a302b76f67108ca7f' 
  AND token = 'LoCRu4kP2pOrGhByzzTpV7oNhsi659LvmtYTSypL/NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}