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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f5da298ad25d2ade8fe396dc5fcf65697c284376fc128052dae6bbf845a6c049' 
  AND token = 'MHobIv5ECHI+ApzJWpUtjMGXOfnqtTT0HmxuXRaZrzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}