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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '40c8ea1871e7abd0c911f8c376d08dbb557156ed1ce885f062763c1f4ad6b0cd' 
  AND token = '59OTTMseqKZfjNh4hA+D2w+tQnELQwazMqoTxbJUXHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}