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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c8a054f85d87b7e721fbc0a9c5e5582bc1504d9e2b45e64217c29910aa780fd' 
  AND token = 'AwAZs0sHPuZdeqinINzuy+2mfMzRHnbFmY23hJpaVpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}