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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '850998216874e6b033cdd7193c65a53e41ed8ec217cd8401bd2b3235cd056243' 
  AND token = '0IVEK2I7cX3SfeQ4q5e8dwwmxWOIj2KRBKcYbi/dZkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}