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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f50ee682c07f44ad77d8af44487607c1f01d9f1b40202e2e4683db3eb15fda80' 
  AND token = 'xzwr/JaBld+AIXRdzIOToOheukDiyGvt4KNdHuRK7Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}