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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5ecb2f4c9c25344046d4c537da33500d7e60641512a1ad6c9654a3da01c6e67' 
  AND token = '9M2G2WdSDy2pfsU/9S2QtFrbmBpF/yA27IdMqSqM/e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}