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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '682635a7c74f89c9df1a300742b46ad6cc6c5388b6aac0a19a8faa39870f10a1' 
  AND token = 'VUlxX0Bx6rQlaMOLVqqW6YnHAVfeiGNUqgzF7YlB46c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}