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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d0f206e692f3cb7a3f25a51710e2434230cf059e6e60eea11cb5779ab4feb50' 
  AND token = 'Y33EhHgyDYEWOoywu6uDInWcdVhfcWvnZO5+KJJCJgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}