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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ccb5225daa7f0baf8a6d75fa0c843c810cb07a0017db3dd022eb03f288208a9b' 
  AND token = 'lnzNvu1ILmbfsTCqoHNmfxC4ysSa+7YXx+nXtY/NNH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}