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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5f9f80788697f5bfa180714abc69cb0e629c8eeaaf99b906232bd3707b91faf' 
  AND token = 'jAxX4MlEz3lTSiixZd9s/mS4XD2oK4ZoUrcw/lCAz0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}