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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4366587eea72a0467410ba50236442ec979e851ada49e14f83b5b74918aa4f80' 
  AND token = 'RtdPrnqOkrK5uCXloiGsGKqzNl9QhHTY9hRfqb4n9aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}