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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad2757d1b95e52c4fc42b93af0384adec46d383749674f1fa41b2ce397019fc4' 
  AND token = '4htp24orE6kn2gqCHQg+96I/3jYFlCHtxIyYLY6Yp/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}