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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2fc5de166b42ef5035284da5e4446e7f7c71ac37477f3510eee91012f7d6721c' 
  AND token = '1usOm5QCtPiuGC9XCNfvx4sPZMCtXKDAyHomB10ZNrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}