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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e509959f3825d9044f7c0c1b8e9ee515b686f847442d3c21d48a0c3845da7aa8' 
  AND token = '3PMpdW8HjtMHcgz8KV83afX8maz4zOk4GbS/PwevtXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}