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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fff89101ce3a64916c4524cace3b0b525f49d3c93e016dedd11026e3645384aa' 
  AND token = '2zzIqf0AFqH2ddQAYXpy89dlmTPcz49e+RQqdb9Py/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}