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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '311278bc6807255e655f229ac76f029022148b474f28901f4e15bca2e56a401f' 
  AND token = '7E6R3qP7TAbpf/3kzI0arJw5eLELlIwkN2c12lYFK5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}