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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '863e34409eabb34fc1518eac1e35e1569892f0206b4e61999933b2086bba1f72' 
  AND token = 'difFYXc8ki/vKR2dde28/g2OGj8W0j3ooxxiRD2TRRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}