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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6ed54a43f8adb52cc08d1bfe9e79484426db5a5cfbc91fee050f29d07c3a64c2' 
  AND token = 'R6MfRR353VRfRFEC/YFRnqNEQJnEWn21U8llwIMk+A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}