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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b479b12713acee6af19d040e20f9a9cc38e0afc157949b9c27c81faa0b5a15e' 
  AND token = 'mFSyhY3CWOOPVYY1M7cgT/RuqWaFYHnsGGjFoWZX4MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}