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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21b3ca2371edd64df8f4f7cf4a53726d38a114bbed516719ec8d34730a1ee436' 
  AND token = 'yV/QYd8wd171kCRuVxQbc8JIbDy/xsfE0uWglchIZLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}