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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2162806f49052c602193e2c00014996400cdc73250f134711e23e6bd97a243f' 
  AND token = '9sB8w2KKr46hSyq9CNeM7pjPN1yUJoo4AN7saoCMRcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}