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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '44d332f294409b445b376551694ba4407e90733044c0573bd7a097577de35b58' 
  AND token = '2xggq8tTk+MUfyEuh01h3g9+frb+IFsjDmHCP1U9mMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}