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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'eb1963e84539f658705aab33d271bef263a00e9c08eb7fa1fbf17fd0d398f1ff' 
  AND token = 'OYUYxxCrA+kNfov8mAfdG3RsFDFiH0AuVcwO2jdG37Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}