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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22f846656a01867abf97ff1570a2c7005601b1c84e4bb5492d1794cc0be7a61b' 
  AND token = 'd8ilnBBen7GxEa+DugSqq1cd8dZeCtdjj9eFXF0CJZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}