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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e4fcd67bc737720e16ea0db90435d1280de4534383f1ab244b21d6dddd046d7e' 
  AND token = 'Q45+smNqOafft3rtuAPaTs6SpRnJvOy8537OKAU02m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}