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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '48f706328626de918fa687a593a2b84762cb36e82f5cd0881e1f47ece7388fca' 
  AND token = 'aW1tjXjT9bzqoTd9+X2tb50lOa+gcXBWxZVE9PiybNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}