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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45bd6600e442e4d76b5887b4b1f0288443706bd2b091d2a8573b0d27100fe750' 
  AND token = 'BFhNA2uF48Yc9g1Kfbt4lqajmh7L8v3xmOgD4Xnmbs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}