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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e246e440de93ebae647b947fa8812d427ffb0f2e3f0ab74ce1bc35647255421c' 
  AND token = 'sy0zeFo1AQKmLTdcW6pRXMwLMxsBdQ/Rnz0PaGmN2p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}