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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '434d1d7b866df07a0301376b7ac13dbc506af538fefc2cc59682e13145a2a166' 
  AND token = 'c7IeO6LbNBSy/1ab0enTnESC3NwWBWmWzcOikUuFo3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}