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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a234da12b90fe292f9473d7ce148b24229e2913975941daa5a36caddbac1297f' 
  AND token = 'IUI2uWFlJTZNUYx8C0O1aHKdP4b8gqtWny5IBxNpHtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}