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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad8aaaa41b589685e84d008ee2406521635716aeea72d97764e88f76a7d6b3b6' 
  AND token = 'NmrBhaS/+vMmV0UPx0EFzQqnZCxM5dlLQFYDDLXRdf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}