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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74a0beb06509521d445ab11f58e05e481830616c1ed502c35cf2951da3118982' 
  AND token = 'i+2syFPWlmPxpfdWXl+AK6NI9HKMbKukHAIFLaiJrQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}