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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '779a7cad09999b375a0200fd3f83d93ad4cc2d10e33b68be842f158f0c4e0f4c' 
  AND token = 'gP2YMKQzyUsz90c0ReqUU3HNKsA8/NpQpvcpCu7fA6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}