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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '445766e11e4c39999444a4b23e9f0cbbdfe58914f1e6050dd2b3ccb7b47ebab1' 
  AND token = 'mdzdS8nhUWWx8+KdM9P+au7wbSxAab7FXx/OaYcRQhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}