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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7d9345a9bb83af51731dc7a186a89642fdce6d5854484043a13c9ac1d1819023' 
  AND token = 'lO0LEZ5PR3mAmJMzvtrWiEHcknyZm6OItlyldt44IEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}