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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f278bb47928e14d8e3e09060f59b36a82916d535c24b11d23708f7070840feb' 
  AND token = '+qpfi5I8/bKkdwwlrv0D0mvjboNiHaEMDYiX8bfBoto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}